mesodermar⁺ 美 索 達

鏢靶式水光 美容院高濃度導入精華

Exclusive“m+” Formula

精華最強配方の力を体験しよう

Exclusive formula
“m+”

MESODERMAR's "m+ formula" is unparalleled in the market, synergizing with the most scientifically-backed anti-aging active ingredients. It unlocks the full potential of skin regeneration, repair, and rejuvenation through cutting-edge innovation.

Plant-derived Exosomes 

  • Natural carriers of bioactive molecules.
  • Enhancing intercellular communication.

  • Directly delivering growth factors to target cells, amplifying the regeneration process.

Plant-derived PDRN

  • Stimulating fibroblast activity and DNA repair pathways.

  • Promoting collagen synthesis and cellular renewal.

Salmon-derived PN

  • Provides DNA fragments to promote cell proliferation.

  • Reducing inflammation and supporting tissue repair.

Plant Exosome Complex

Exosomes derived from plants. These tiny vesicles contain various bioactive components, such as proteins, nucleic acids, metabolites, and lipids, and possess multiple potential health benefits, including antioxidant, anti-inflammatory, and even tissue regeneration promotion.

Exosomes are small membrane vesicles released by cells, with diameters ranging from 30 to 150 nanometers. They have diverse biological functions. They play a crucial role in intercellular communication and are involved in many biological processes.

5 Significant Advantages

  • Modulating immune cells

  • Anti-inflammatory action

  • Promoting wound healing

  • Preventing cell apoptosis

  • Antioxidant properties

Plant-derived PDRN
Polydeoxyribonucleotide

PDRN (polydeoxyribonucleotide) is a biopolymer extracted from plant DNA. Its regenerative and healing properties make it popular in both cosmetic and medical applications.

Regenerative properties
PDRN promotes tissue repair and regeneration by stimulating cell proliferation, accelerating the healing process.

Anti-aging effects
PDRN helps improve skin elasticity, reduce wrinkles, and enhance overall skin texture, making it a common ingredient in anti-aging skincare products.

Cell repair
By promoting DNA synthesis and cellular repair mechanisms, PDRN helps maintain healthy skin and prevent premature aging.

Anti-inflammatory action
PDRN has anti-inflammatory properties, which can help reduce skin redness and irritation.

Wound healing
Studies show it can accelerate wound healing and improve skin recovery after injury or surgery.

Salmon-derived PN
Polynucleotides

PN (polynucleotide) is a biomolecule composed of multiple nucleotide units, typically found in DNA and RNA. PN has various applications in biology and medicine, particularly in cell therapy and regenerative medicine.

PN is an important biomolecule with diverse biological activities, widely used in skincare and medical fields.

5 Significant Advantages

  • Key features
    Structural composition
    PN is formed by nucleotides linked together by phosphodiester bonds, creating a long chain structure.

  • Biological activity
    PN has the ability to promote cell proliferation, repair, and regeneration, which is particularly important for promoting tissue healing and improving skin condition.

  • Wide applications
    In medicine, PN is used for wound healing, anti-aging treatments, and other regenerative medicine applications.

  • High safety
    PN is generally considered safe and non-toxic to the human body, suitable for various therapeutic and skincare products.

  • Application areas
    Skincare products: Used in anti-aging and skin repair serums. Medical treatments: Used in wound healing and cell regeneration therapies.

MESO-1
Firm Lift & Wrinkle Care

  • Hydration Promoting－Increases skin cell water retention, promoting fullness and a youthful appearance.

    Stimulating Collagen Production－Enhances collagen synthesis, improving skin elasticity and firmness.

    Promoting Cellular Regeneration－Promotes skin cell renewal, helping repair damaged skin and reduce the appearance of wrinkles.

    Reduce Inflammation－Contains anti-inflammatory properties, helping soothe irritated skin and promote an even skin tone.

    Nutrient Delivery－Provides essential nutrients and growth factors to support overall skin health.

  • Wrinkle Reduction－Actively reduces wrinkle depth and appearance, promoting skin repair mechanisms.

    Muscle Relaxation－Certain peptides, such as Acetyl Hexapeptide-8, mimic the effects of botulinum toxin, reducing muscle contractions that contribute to wrinkle formation.

    Firming and Lifting－Enhances skin firmness by stimulating the production of collagen and elastin.

    Skin Barrier Support－Strengthening the skin barrier, improving moisture retention, and providing resistance to environmental stressors.

    Anti-Inflammatory Effects－Reduces inflammation, promoting a more even skin tone and texture.

  • Antioxidant Protection－Rich in antioxidants, these extracts protect the skin from oxidative stress and free radical damage.

    Soothing Properties－Soothes irritated skin, reduces redness and swelling, and enhances overall skin comfort.

    Improved Hydration－Improves skin's moisture levels, promoting a healthy and hydrated complexion.

    Brightening Effect－Certain extracts help brighten the complexion and reduce the appearance of pigmentation.

    Nutrient-Rich－Provides vitamins and minerals, nourishing the skin and supporting its natural functions.

MESO-2
Blemish & Pore Soothing

  • Anti-inflammatory Action－Sodium ascorbyl phosphate and dipotassium glycyrrhizate help reduce skin inflammation and irritation.

    Exfoliation－Glycolic acid promotes the shedding of dead skin cells, preventing pore blockage and reducing acne.

    Improved Skin Barrier－Strengthens the skin's barrier function, helping to retain moisture and maintain overall skin health.

    Antioxidant Protection－Sodium ascorbyl phosphate converts to vitamin E, neutralizing reactive oxygen species and protecting skin cells from oxidative stress.

    Soothing Effect－Dipotassium glycyrrhizate provides a soothing effect, suitable for sensitive skin.

  • Powerful Anti-inflammatory Effect－Many of these extracts, particularly Centella asiatica and stonewort, are known for their potent anti-inflammatory properties.

    Immunomodulatory Effects－These extracts help regulate the immune response, proving effective for conditions like atopic dermatitis and psoriasis.

    Acne Reduction－Stonewort extract has been clinically proven to reduce acne lesions and promote emotional well-being.

    Antioxidant Activity－Extracts of green tea and rosemary provide significant antioxidant protection against oxidative stress.

    Brightening Effect－Licorice root and lemon balm extracts help brighten the complexion and reduce pigmentation.

MESO-3
Reborn & Repair

  • Multi-layer Hydration－Provides moisture at different skin depths, ensuring comprehensive moisture retention.

    Hydration Barrier Formation－Hydroxypropyltrimonium hyaluronate forms a protective moisture veil, preventing transepidermal water loss

    Sustained Hydration－Crosslinked sodium hyaluronate-2 provides 24-hour hydration, protecting skin from environmental stress.

    Enhanced Elasticity－Sodium acetylated hyaluronate improves skin elasticity and barrier function, promoting a youthful appearance.

    Surface Nourishment－Sodium hyaluronate nourishes the stratum corneum, enhancing overall skin texture and smoothness

  • Skin barrier repair－Ceramides replenish the skin's natural lipid barrier, preventing moisture loss and enhancing hydration.

    Improved skin texture－By filling the gaps in the stratum corneum, it promotes smoother skin, reducing dryness and peeling.

    Supports skin elasticity－Helps improve skin elasticity, preventing sagging and promoting a youthful appearance.

    Strengthening skin resilience－Strengthening the skin's defense against environmental damage, reducing sensitivity and irritation.

    Moisture retention－Helps lock in moisture within the skin, ensuring all-day hydration.

  • Enhanced Moisturization－Supports collagen and elastin, providing mild anti-aging and anti-wrinkle effects.

    EGF action, promoting epidermal cell proliferation－Enhances skin regeneration and moisturization to support youthful, nourished skin.

    Protects against environmental stressors (pollution and UV rays).

    Prevents and reduces eczema and inflammation.－Reduces fine lines, wrinkles, dark spots, and hyperpigmentation, helping to brighten the complexion. Nourishes, moisturizes, and improves skin elasticity, while also increasing collagen production.

    Resisting environmental damage and slowing visible aging signs.－Fades dark spots and sunspots caused by sun exposure, strengthens the skin barrier and resists oxidative damage.

  • Antioxidant Protection－Provides powerful antioxidant effects, neutralizing free radicals and reducing oxidative stress on the skin.

    Enhanced Hydration－Improves the skin's ability to retain moisture, boosting overall hydration levels.

    Wound Healing Support－Promotes skin repair and regeneration, assisting in the healing of damaged skin.

    Anti-inflammatory Properties－Reduces inflammation, suitable for sensitive or irritated skin conditions.

    Improved skin elasticity－Supports the synthesis of collagen and elastin, enhancing skin firmness and elasticity.

  • Deep Hydration－Amino acids attract and retain moisture, enhancing the skin's hydration from within.

    Skin Repair and Regeneration－Supports the skin's natural healing process, promoting the repair of damaged tissues.

    Strengthening Skin barrier Function－Strengthening the skin barrier, increasing resistance to environmental stress.

    Nutrient Supply－Provides essential nutrients needed for healthy skin, supporting cellular function and metabolism.

    Soothing Properties－Helps soothe irritated skin, reducing redness and swelling, and promoting an even skin tone.

Scientific Evidence